Thursday, 26 May 2016

What is MAO?

Monoamine Oxidase (MAO)
You may have heard or ready about the acronym called MAOI. This stands for 'monoamine oxidase inhibitor' and is to inhibit monoamine oxidase that is the primary enzyme within the body that breaks down the DMT compound. So by inhibiting these enzymes the DMT will remain in the body for a much longer period of time.

There are two classes of MAO; MAO-A and MAO-B. Inhibitors act differently on these classes of compounds, inhibitors that act on MAO-A are safer because they are reversible, which means they detach from the MAO-A within 36hrs.

Unlike MAO-B inhibitors that can take up to 2 weeks to be removed from the system, due to the cells requirement to synthesize new enzymes. MAOI’s are typically used to treat depression, Parkinson’s disease, Hodgkin’s lymphoma and others, and are contained within such drugs as Marplan, Moclobemide, Nardil, Procarbazine.

There are four main concerns associated with an MAOI:
1. Once the MAOI blocks the MAO enzyme it can let harmful tyramines and tryptamines into the blood stream, which can lead to serious cardiac or psychiatric emergencies. This means a special diet is required in order to remove potential toxins from being ingested into the body.

2. As there are two classes of MAO’s, it is important to know which inhibitor to ingest, know the effects on the body and ensure an appropriate diet is maintained throughout.

3. Interactions with other chemicals being taken, such as blood pressure medication, flu medication, MDMA, SSRI’s can increase the risk of serious issues or even death

4. MAOI's also have profound effects on the brain, which can be felt when taken. Be aware of the effects and how they may be similar or how they differ from other chemicals that you intake into your body.

Due to the way in which the MAOI works on the system it is extremely important to be aware of your diet and eliminate the intake of tryptamines (except for DMT) and especially tyramines. We have not previously raised a risk that tyramines have on the brain and secondary effects on the body, but they significantly impact the regulation of blood pressure, which under some situations can lead to serious issues that require hospitalisation and in extreme cases can lead to death.

Source of MAOI
In order to ingest the MAOI that targets MAO-A, it is safer to ingest a capsulated form of powdered Syrian Rue Seed.

You can quite easily purchase powdered Syrian Rue Seed via eBay and you will only require very small quantities.

Make sure you do your research before taking any MAOIs - they can be deadly.

Note: If you chose to take an MAOI together with DMT, you must understand the risks and manage them effectively - there have been reported deaths due to the use of MAOIs.

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